Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B1
Variant:p.N128Y
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SLCO1B1

NM_006446.5:p.N128Y

Associated Papers

Stoichiometric transport of estrone 3-sulfate among genetic variants of OATP1A2 and OATP2B1 and structural analysis by molecular dynamics simulation: Impairment of gating mechanism in the unstable inward-open conformation of OATP2B1 (Asp215Val) significantly suppress the transport activity.

Akiyoshi T et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025

Impact of genetic variants in the solute carrier (SLC) genes encoding drug uptake transporters on the response to anticancer chemotherapy.

Marin JJG et al.

Cancer Drug Resistance (alhambra, Calif.), 2024

Genetic variability and population diversity of the human SLCO (OATP) transporter family.

Zhang B et al.

Pharmacological Research, 2019

Implications of genetic polymorphisms in drug transporters for pharmacotherapy.

Kerb R

Cancer Letters, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."