Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B1
Variant:p.S137S
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SLCO1B1

NM_006446.5:p.S137S

Associated Papers

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc6.xlsx › Sheet1

Atorvastatin-associated myotoxicity: A toxicokinetic review of pharmacogenetic associations to evaluate the feasibility of precision pharmacotherapy.

Hoste E et al.

Clinical Biochemistry, 2024

Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidemia.

Chen C et al.

Pharmacogenomics and Personalized Medicine, 2024

SLCO1B1 and SLC10A1 polymorphism and plasma rifampin concentrations in patients with co-morbidity tuberculosis-diabetes mellitus in Baja California, Mexico.

Perea-Jacobo R et al.

Tuberculosis (edinburgh, Scotland), 2022

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms.

Choudhuri S et al.

Toxicology and Applied Pharmacology, 2020

Association Between SLCO1B1 Gene T521C Polymorphism and Statin-Related Myopathy Risk: A Meta-Analysis of Case-Control Studies.

Hou Q et al.

Medicine, 2015

Frequencies of single-nucleotide polymorphisms and haplotypes of the SLCO1B1 gene in selected populations of the western balkans.

Grapci AD et al.

Balkan Journal of Medical Genetics : Bjmg, 2015

No impact of SLCO1B1 521T>C, 388A>G and 411G>A polymorphisms on response to statin therapy in the Greek population.

Giannakopoulou E et al.

Molecular Biology Reports, 2014

OATP1B1-related drug-drug and drug-gene interactions as potential risk factors for cerivastatin-induced rhabdomyolysis.

Tamraz B et al.

Pharmacogenetics and Genomics, 2013

Influence of the functional polymorphisms in the organic anion transporting polypeptide 1B1 in the susceptibility to colorectal cancer.

Ozhan G et al.

Genetic Testing and Molecular Biomarkers, 2013

Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.

Fahrmayr C et al.

Drug Metabolism Reviews, 2010

Comparison of SLCO1B1 sequence variability among German, Turkish, and African populations.

Mwinyi J et al.

European Journal of Clinical Pharmacology, 2008

The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members.

Seithel A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2008

Pharmacogenetics of SLCO1B1: haplotypes, htSNPs and hepatic expression in three distinct Asian populations.

Jada SR et al.

European Journal of Clinical Pharmacology, 2007

Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population.

Pasanen MK et al.

European Journal of Clinical Pharmacology, 2006

MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype.

Lamba J et al.

Clinical Pharmacology and Therapeutics, 2006

Pharmacogenomics of human OATP transporters.

König J et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2006

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans.

Tirona RG et al.

The Journal of Biological Chemistry, 2001

Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.

Meyer zu Schwabedissen HE et al.

Molecular Pharmaceutics, 0

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