Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B1
Variant:p.R152K
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SLCO1B1

NM_006446.5:p.R152K

Associated Papers

PharmVar GeneFocus: SLCO1B1.

Ramsey LB et al.

Clinical Pharmacology and Therapeutics, 2023

Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokinetics.

Nie Y et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake.

Niemi M et al.

Pharmacological Reviews, 2011

Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.

Fahrmayr C et al.

Drug Metabolism Reviews, 2010

Comparison of SLCO1B1 sequence variability among German, Turkish, and African populations.

Mwinyi J et al.

European Journal of Clinical Pharmacology, 2008

Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C.

Seithel A et al.

Molecular Genetics and Genomics : Mgg, 2008

The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members.

Seithel A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2008

Pharmacogenetics of SLCO1B1: haplotypes, htSNPs and hepatic expression in three distinct Asian populations.

Jada SR et al.

European Journal of Clinical Pharmacology, 2007

Pharmacogenomics of human OATP transporters.

König J et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2006

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis.

Nozawa T et al.

The Journal of Pharmacology and Experimental Therapeutics, 2002

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans.

Tirona RG et al.

The Journal of Biological Chemistry, 2001

Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.

Meyer zu Schwabedissen HE et al.

Molecular Pharmaceutics, 0

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