Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B1
Variant:p.V174A
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SLCO1B1

NM_006446.5:p.V174A

Associated Papers

HLA DRB1*01 and *04 Predisposition to Rheumatoid Arthritis and Polymorphisms of the SLCO1B1, MTHFR and PNPLA3 Genes Are Not Associated with Fatty Liver and Hepatotoxicity.

Zekić T et al.

Journal of Clinical Medicine, 2026

Rapid and ultrasensitive point of care test for SLCO1B1 rs4149056 SNP detection using RNase H2 assisted Tetra-ARMS RPA combined with lateral flow strip.

Jiang Y et al.

Talanta, 2026

Clinical genetic variation across Hispanic populations in the Mexican Biobank.

Barberena-Jonas C et al.

Nature Medicine, 2026

Intrinsic Factors Influencing Simvastatin and Simvastatin Acid Pharmacokinetics: Age-Related Studies in Thai Adults and Cross-Population Comparisons.

Srimatimanon T et al.

Clinical and Translational Science, 2026

Association of CYP2C19 Single Nucleotide Polymorphism With Hemorrhagic Cystitis After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation.

Zhang W et al.

Clinical Transplantation, 2026

Integration of metabolomic and genetic data reveals novel variants underpinning the human metabolome: the Coronary Artery Risk Development in Young Adults (CARDIA) study.

Krishnan M et al.

Medrxiv : the Preprint Server for Health Sciences, 2026

41646814 (PubMed )
Supplement: media-2.xlsx › TableS8

Association between SLCO1B1, apolipoprotein E and ABCG2 genes and lipid response to rosuvastatin: a meta-analysis.

Li J et al.

Pharmacogenetics and Genomics, 2026

MTX pathway gene variants, erythrocyte methotrexate polyglutamates, and treatment outcomes in rheumatoid arthritis.

Wang P et al.

Biomolecules & Biomedicine, 2026

Impact of SLCO1B1 Polymorphism and Vitamin D Status on Statin Efficacy and Tolerability in Postmenopausal Women.

Marušić R et al.

Biomedicines, 2026

Analysis of the association between SLCO1B1 gene polymorphisms and coronary heart disease risk in southern Han Chinese population and statin responses in the elderly.

Long Y et al.

Frontiers in Cardiovascular Medicine, 2026

The impact of single nucleotide polymorphisms on the absorption, distribution, metabolism, and excretion of dietary (poly)phenols: a critical systematic review.

Tosi N et al.

Food & Function, 2025

Effects of nonsense genetic variants on OATP1B1 expression and transport activity in vitro.

Kiander W et al.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 2025

An Update to the Clinical Pharmacogenetics Implementation Consortium (CPIC) SLCO1B1 Allele Functionality Table Leveraging Evidence from Participants of Predominantly Sub-Saharan African Ancestry.

Oni-Orisan A et al.

Clinical Pharmacology and Therapeutics, 2025

Leveraging Genome-wide Association Studies to Identify Pathogenic Variants for Breast Cancer Among Multiple Continents.

Admanegara PPS et al.

Anticancer Research, 2025

Genetic landscape and therapeutic evolution of cyclophosphamide: spotlight on breast cancer.

Cao J et al.

Journal of Chemotherapy (florence, Italy), 2025

Genetic and epigenetic architectures of stroke: Insights from GWAS to precision medicine.

Shehjar F et al.

Neurochemistry International, 2025

Methotrexate gene polymorphisms link to toxicity but not pharmacokinetics in Chinese adults and adolescents with acute lymphoblastic leukemia.

Bing H et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025

Retrospective Evaluation of the Impact of SLCO1B1 Variation on Statin Effectiveness.

Ahmed Feldman M et al.

Journal of Personalized Medicine, 2025

Impact of Complex Genetic and Drug-Drug Interactions on Tamoxifen Metabolism and Efficacy.

Saad I et al.

Journal of Personalized Medicine, 2025

Genome-wide screening of pharmacogenomic biomarkers in jordanian patients with genetic disorders.

Jarrar Y et al.

The Pharmacogenomics Journal, 2025

Whole-Genome Sequencing Reveals a Novel GATA2 Mutation in Lower-Grade Glioma: Bioinformatics Analysis of Functional and Therapeutic Implications.

Handoko et al.

Cancers, 2025

41154393 (PubMed )
Supplement: cancers-17-03338-s001.zip › Table_S1._SNV_Analysis.xlsx › SNV_Analysis

Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population.

Xu JX et al.

World Journal of Cardiology, 2025

XBP1 expression in pancreatic islet cells is associated with poor glycaemic control especially in young non-obese onset diabetes across ancestries.

Siddiqui MK et al.

Communications Medicine, 2025

40993285 (PubMed )
Supplement: 43856_2025_1076_MOESM1_ESM.pdf

Exploratory Study on Genetic Variants Related to Hydatidosis Susceptibility and Albendazole Pharmacogenetics in the Cusco Region in Peru.

Jaramillo-Valverde L et al.

Frontiers in Bioscience (scholar Edition), 2025

Relevance of selected pharmacogenetic polymorphisms to bleeding and thromboembolic risks in Chinese patients taking direct-acting oral anticoagulants.

Wang D et al.

British Journal of Clinical Pharmacology, 2025

Influence of pharmacokinetics-related gene polymorphisms on plasma levels of clozapine and its metabolites in Japanese patients with schizophrenia.

Kinoshita S et al.

Pcn Reports : Psychiatry and Clinical Neurosciences, 2025

Pharmacogenomics in cardiac therapy: Personalizing treatment for heart health.

Naderi N et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2025

Association of ABCB1 G2677T polymorphism with atorvastatin lipid efficacy and extended prognosis in patients with cerebral ischemic stroke.

Tian Y et al.

Scientific Reports, 2025

Physiologically-based pharmacokinetic modeling of rosuvastatin in Chinese: Predicting the impact of SLCO1B1 and ABCG2 genetic variants and hepatic impairment on drug exposure.

Li L et al.

Journal of Pharmaceutical Sciences, 2025

Unveiling hidden risks: pharmacogenetic insights from a cross-sectional study of statin therapy in the Indian population.

Naushad SM et al.

Pharmacological Reports : Pr, 2025

Association of SLCO1B3 and SLCO1B1 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients.

Magadmi R et al.

Pharmaceuticals (basel, Switzerland), 2025

Clinical impact of pharmacogenetic risk variants in a large chinese cohort.

Wei CY et al.

Nature Communications, 2025

Pharmacogenetic Biomarkers of Ibrutinib Response and Toxicity in Chronic Lymphocytic Leukemia: Insights from an Observational Study.

Pérez-Gómez N et al.

Pharmaceuticals (basel, Switzerland), 2025

Identification and Clinical Evaluation of Potential Biomarkers for Breast Cancer Resistance Protein (BCRP/ABCG2).

Riselli AM et al.

Clinical Pharmacology and Therapeutics, 2025

Comparative analysis of the single-molecule transport kinetics of OATP1B1 genetic variants.

Tsujii K et al.

Journal of Pharmacological Sciences, 2025

Effects of SCT genetic polymorphisms on methotrexate concentrations and toxicities in Chinese children with acute lymphoblastic leukemia.

Li M et al.

Leukemia & Lymphoma, 2025

Identification of Genetic Variants Associated with Pravastatin and Pitavastatin Pharmacokinetics.

Mykkänen AJH et al.

Clinical Pharmacology and Therapeutics, 2025

SLCO1B1 Functional Variants, Bilirubin, Statin-Induced Myotoxicity, and Recent Sub-Saharan African Ancestry: A Precision Medicine Health Equity Study.

Haldar T et al.

Clinical Pharmacology and Therapeutics, 2025

Susceptibility of RUNX1 promoter rs2071029 polymorphism to adjuvant chemotherapy-induced neutropenia in CRC.

Luo X et al.

Biomarkers in Medicine, 2025

Triple Non-Statin Therapy with Ezetimibe, Inclisiran, and Bempedoic Acid in Patients with Genetically Confirmed Statin-Induced Rhabdomyolysis: A Dual Case Report.

Dodulík J et al.

Pharmaceuticals (basel, Switzerland), 2025

Silencing drug transporters in human primary muscle cells modulates atorvastatin pharmacokinetics: A pilot study.

Hoste E et al.

British Journal of Pharmacology, 2025

Impacts of Pharmacokinetic Gene Polymorphisms on Steady-State Plasma Concentrations of Simvastatin in Thai Population.

Tipnoppanon S et al.

Clinical and Translational Science, 2025

Pharmacogenomic insights into atorvastatin and rosuvastatin adverse effects: a prospective observational study in the UAE's multiethnic population.

Alqasrawi MN et al.

Human Genomics, 2025

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between SLCO1B1 and statins and CYP2C9 and sulfonylureas.

Wolthuis DFGJ et al.

European Journal of Human Genetics : Ejhg, 2025

The Impact of Organic Anion-Transporting Polypeptide (OATP) Variants on the Side Effects of Direct-Acting Antivirals in Hepatitis C Patients.

Altintas Z et al.

Cureus, 2025

Association of SLCO1B1 genetic variants with neonatal hyperbilirubinemia: a consolidated analysis of 36 studies.

Talebi H et al.

Bmc Pediatrics, 2025

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."