Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B1
Variant:p.L191L
Back to variants list

SLCO1B1

NM_006446.5:p.L191L

Associated Papers

Contrastive sequence signatures between the both sides of a recombination spot reveal an adaptation at PPARD locus from standing variation for pleiotropy since out-of-Africa dispersal.

Shou W et al.

Bmc Genomics, 2025

40307732 (PubMed )
Supplement: 12864_2025_11620_MOESM2_ESM.xlsx › TS5

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc6.xlsx › Sheet1

When the same treatment has different response: The role of pharmacogenomics in statin therapy.

Zheng E et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidemia.

Chen C et al.

Pharmacogenomics and Personalized Medicine, 2024

SLCO1B1 and SLC10A1 polymorphism and plasma rifampin concentrations in patients with co-morbidity tuberculosis-diabetes mellitus in Baja California, Mexico.

Perea-Jacobo R et al.

Tuberculosis (edinburgh, Scotland), 2022

Pharmacogenetics of Drugs Used in the Treatment of Cancers.

Franczyk B et al.

Genes, 2022

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms.

Choudhuri S et al.

Toxicology and Applied Pharmacology, 2020

Study of Caspase 8 mutation in oral cancer and adjacent precancer tissues and implication in progression.

Singh R et al.

Plos One, 2020

32492030 (PubMed )
Supplement: pone.0233058.s001.xlsx › RADS18

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

Pharmacogenetic Analysis of the Model-Based Pharmacokinetics of Five Anti-HIV Drugs: How Does This Influence the Effect of Aging?

Chen J et al.

Clinical and Translational Science, 2018

Influence of SLCO1B1 polymorphisms on atorvastatin efficacy and safety in Macedonian subjects.

Mladenovska K et al.

Die Pharmazie, 2017

Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder.

Medhasi S et al.

Neuropsychiatric Disease and Treatment, 2016

Effects of single nucleotide polymorphisms and haplotypes of the SLCO1B1 gene on the pharmacokinetic profile of atorvastatin in healthy Macedonian volunteers.

Daka A et al.

Die Pharmazie, 2015

Frequencies of single-nucleotide polymorphisms and haplotypes of the SLCO1B1 gene in selected populations of the western balkans.

Grapci AD et al.

Balkan Journal of Medical Genetics : Bjmg, 2015

Establishment of an expression platform of OATP1B1 388GG and 521CC genetic polymorphism and the therapeutic effect of tamoxifen in MCF-7 cells.

Pu Z et al.

Oncology Reports, 2015

Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex.

Prasad B et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2014

OATP1B1-related drug-drug and drug-gene interactions as potential risk factors for cerivastatin-induced rhabdomyolysis.

Tamraz B et al.

Pharmacogenetics and Genomics, 2013

CYP2C9*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics.

Zhou Q et al.

Die Pharmazie, 2013

Simvastatin pharmacokinetics in healthy Chinese subjects and its relations with CYP2C9, CYP3A5, ABCB1, ABCG2 and SLCO1B1 polymorphisms.

Zhou Q et al.

Die Pharmazie, 2013

ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics.

Zhou Q et al.

Die Pharmazie, 2013

CYP2C9*3(1075A>C), MDR1 G2677T/A and MDR1 C3435T are determinants of inter-subject variability in fluvastatin pharmacokinetics in healthy Chinese volunteers.

Zhou Q et al.

Arzneimittel-forschung, 2012

The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins.

Hua WJ et al.

Cardiovascular Therapeutics, 2012

Genotyping of OATP2 Variants in a Group of Malaysian Neonates Using High-Resolution Melting Analysis.

Wong FL et al.

Bioresearch Open Access, 2012

Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.

Fahrmayr C et al.

Drug Metabolism Reviews, 2010

OATP1B1 388A>G polymorphism and pharmacokinetics of pitavastatin in Chinese healthy volunteers.

Wen J et al.

Journal of Clinical Pharmacy and Therapeutics, 2010

The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members.

Seithel A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2008

Pharmacogenetics of SLCO1B1: haplotypes, htSNPs and hepatic expression in three distinct Asian populations.

Jada SR et al.

European Journal of Clinical Pharmacology, 2007

Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population.

Pasanen MK et al.

European Journal of Clinical Pharmacology, 2006

Pharmacogenomics of human OATP transporters.

König J et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2006

Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.

Meyer zu Schwabedissen HE et al.

Molecular Pharmaceutics, 0

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."