Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B1
Variant:p.M233I
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SLCO1B1

NM_006446.5:p.M233I

Associated Papers

Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms.

Choudhuri S et al.

Toxicology and Applied Pharmacology, 2020

Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokinetics.

Nie Y et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

SLCO1A2, SLCO1B1 and SLCO2B1 polymorphisms influences chloroquine and primaquine treatment in Plasmodium vivax malaria.

Sortica VA et al.

Pharmacogenomics, 2017

28975866 (PubMed )
Supplement: pgs-18-1401-s1.docx

Functional consequences of genetic variations in the human organic anion transporting polypeptide 1B3 (OATP1B3) in the Korean population.

Chae YJ et al.

Journal of Pharmaceutical Sciences, 2012

Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity.

Schwarz UI et al.

Pharmacogenetics and Genomics, 2011

The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members.

Seithel A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2008

Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics.

Smith NF et al.

Clinical Pharmacology and Therapeutics, 2007

Pharmacogenomics of human OATP transporters.

König J et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2006

Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.

Meyer zu Schwabedissen HE et al.

Molecular Pharmaceutics, 0

The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literature.

Anabtawi N et al.

Expert Opinion on Drug Metabolism & Toxicology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."