Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B1
Variant:p.I499V
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SLCO1B1

NM_006446.5:p.I499V

Associated Papers

A gene risk score using missense variants in SLCO1B1 is associated with earlier onset statin intolerance.

Bigossi M et al.

European Heart Journal. Cardiovascular Pharmacotherapy, 2023

37253618 (PubMed )
Supplement: pvad040_supplemental_file.docx

Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.

Dagli-Hernandez C et al.

Pharmaceutics, 2022

35631530 (PubMed )
Supplement: pharmaceutics-14-00944-s001.zip › pharmaceutics-1634615-supplementary.pdf

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM4_ESM.xlsx › Novel_Previously_described_var.

Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment.

Pernaute-Lau L et al.

Antimicrobial Agents and Chemotherapy, 2021

SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function.

Zhang L et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021

Genetic variability and population diversity of the human SLCO (OATP) transporter family.

Zhang B et al.

Pharmacological Research, 2019

Interindividual and interethnic variability in drug disposition: polymorphisms in organic anion transporting polypeptide 1B1 (OATP1B1; SLCO1B1).

Lee HH et al.

British Journal of Clinical Pharmacology, 2017

Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake.

Niemi M et al.

Pharmacological Reviews, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."