Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B3
Variant:p.S112A
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SLCO1B3

NM_019844.4:p.S112A

Associated Papers

Association Study of OATP1B3 Polymorphisms on Hepatic Uptake and Drug-Drug Interaction In Vitro.

Yang Z et al.

Acs Omega, 2025

Association of SLCO1B3 and SLCO1B1 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients.

Magadmi R et al.

Pharmaceuticals (basel, Switzerland), 2025

Impacts of Pharmacokinetic Gene Polymorphisms on Steady-State Plasma Concentrations of Simvastatin in Thai Population.

Tipnoppanon S et al.

Clinical and Translational Science, 2025

The Impact of Organic Anion-Transporting Polypeptide (OATP) Variants on the Side Effects of Direct-Acting Antivirals in Hepatitis C Patients.

Altintas Z et al.

Cureus, 2025

Pharmacogenetics in Tuberculosis-HIV Coinfected Populations: A Systematic Review of Genetic Variants Influencing Antiretroviral and Anti-Tuberculosis Drug Response.

Hardi H et al.

Journal of Multidisciplinary Healthcare, 2025

A mutation in CCDC91, Homo sapiens coiled-coil domain containing 91 protein, cause autosomal-dominant acrokeratoelastoidosis.

Zhu Y et al.

European Journal of Human Genetics : Ejhg, 2024

38627542 (PubMed )
Supplement: 41431_2024_1573_MOESM3_ESM.xlsx › Sheet1

Gene polymorphisms and thyroid hormone signaling: implication for the treatment of hypothyroidism.

Penna GC et al.

Endocrine, 2024

Atorvastatin-associated myotoxicity: A toxicokinetic review of pharmacogenetic associations to evaluate the feasibility of precision pharmacotherapy.

Hoste E et al.

Clinical Biochemistry, 2024

Do Gene Polymorphisms Play a Role in Newborn Hyperbilirubinemia?

Hakan N et al.

Balkan Journal of Medical Genetics : Bjmg, 2023

Association between CYP3A4/CYP3A5 genetic polymorphisms and treatment outcomes of atorvastatin worldwide: is there enough research on the Egyptian population?

Maslub MG et al.

European Journal of Medical Research, 2023

Loss of Function ABCG2 c.421C>A (rs2231142) Polymorphism Increases Steady-State Exposure to Mycophenolic Acid in Stable Renal Transplant Recipients: An Exploratory Matched Cohort Study.

Borić-Bilušić AA et al.

Advances in Therapy, 2023

SLCO1B3 T334G polymorphisms and mycophenolate mofetil-related adverse reactions in kidney transplant recipients.

Zhong J et al.

Pharmacogenomics, 2023

Development of Novel Mass Spectrum-Based Assay for Simultaneous Detection of 36 Variants in the 14 Pharmacogenetic Genes for the Japanese Population.

Yamamoto N et al.

Biological & Pharmaceutical Bulletin, 2023

SLCO1B1 c.521T>C gene polymorphism decreases hypoglycemia risk in sulfonylurea-treated type 2 diabetic patients.

Ragia G et al.

Drug Metabolism and Personalized Therapy, 2022

Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation.

Nies AT et al.

Pharmacology & Therapeutics, 2022

Use of Pharmacogenetics to Optimize Immunosuppressant Therapy in Kidney-Transplanted Patients.

Urzì Brancati V et al.

Biomedicines, 2022

Impacts of SNPs on adverse events and trough concentration of imatinib in patients with gastrointestinal stromal tumors.

Maekawa K et al.

Drug Metabolism and Pharmacokinetics, 2022

Atorvastatin population pharmacokinetics in a real-life setting: Influence of genetic polymorphisms and association with clinical response.

Stillemans G et al.

Clinical and Translational Science, 2022

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry.

Bateman NW et al.

Iscience, 2022

35036865 (PubMed )
Supplement: mmc2.xlsx › SupplementalTable1A

Genotypic and phenotypic landscapes of 51 pharmacogenes derived from whole-genome sequencing in a Thai population.

Wankaew N et al.

Plos One, 2022

Association of Drug-Metabolizing Enzyme and Transporter Gene Polymorphisms and Lipid-Lowering Response to Statins in Thai Patients with Dyslipidemia.

Vanwong N et al.

Pharmacogenomics and Personalized Medicine, 2022

Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Silgado-Guzmán DF et al.

Frontiers in Pharmacology, 2022

35846994 (PubMed )
Supplement: Table1.xlsx › Hoja1

Association of SLC22A1,SLCO1B3 Drug Transporter Polymorphisms and Smoking with Disease Risk and Cytogenetic Response to Imatinib in Patients with Chronic Myeloid Leukemia.

Mohammadi F et al.

Laboratory Medicine, 2021

Effect of efavirenz-based ART on the pharmacokinetics of rifampicin and its primary metabolite in patients coinfected with TB and HIV.

Sundell J et al.

The Journal of Antimicrobial Chemotherapy, 2021

Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing.

Yoon JG et al.

Transplantation, 2021

The Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid: Systematic Review and Meta-analysis.

Na Takuathung M et al.

Clinical Pharmacokinetics, 2021

Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir.

van Eijk M et al.

The Pharmacogenomics Journal, 2021

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM10_ESM.xlsx › Supplementary_Data_7

Late response to rosuvastatin and statin-related myalgia due to SLCO1B1, SLCO1B3, ABCB11, and CYP3A5 variants in a patient with Familial Hypercholesterolemia: a case report.

Dagli-Hernandez C et al.

Annals of Translational Medicine, 2021

Role of Genetic Variations in the Hepatic Handling of Drugs.

Marin JJG et al.

International Journal of Molecular Sciences, 2020

Thyroid Hormone Transporters.

Groeneweg S et al.

Endocrine Reviews, 2020

Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokinetics.

Nie Y et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

The influence of single-nucleotide polymorphisms on overall survival and toxicity in cabazitaxel-treated patients with metastatic castration-resistant prostate cancer.

Belderbos BPS et al.

Cancer Chemotherapy and Pharmacology, 2020

Impact of SLCO1B3 polymorphisms on clinical outcomes in lung allograft recipients receiving mycophenolic acid.

Tague LK et al.

The Pharmacogenomics Journal, 2020

Effects of Trough Concentration and Solute Carrier Polymorphisms on Imatinib Efficacy in Chinese Patients with Chronic Myeloid Leukemia.

Wang Q et al.

Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society for Pharmaceutical Sciences, Societe Canadienne Des Sciences Pharmaceutiques, 2020

A Pharmacogenomic Dissection of a Rosuvastatin-Induced Rhabdomyolysis Case Evokes the Polygenic Nature of Adverse Drug Reactions.

Calderon-Ospina CA et al.

Pharmacogenomics and Personalized Medicine, 2020

Association of the Trough, Peak/Trough Ratio of Imatinib, Pyridine-N-Oxide Imatinib and ABCG2 SNPs 34 G>A and SLCO1B3 334 T>G With Imatinib Response in Egyptian Chronic Myeloid Leukemia Patients.

Omran MM et al.

Frontiers in Oncology, 2020

Identification of a novel somatic mutation of POU6F2 by whole-genome sequencing in prolactinoma.

Miao Y et al.

Molecular Genetics & Genomic Medicine, 2019

Enantiospecific Pharmacogenomics of Fluvastatin.

Hirvensalo P et al.

Clinical Pharmacology and Therapeutics, 2019

Inter-Individual Variability in Xenobiotic-Metabolizing Enzymes: Implications for Human Aging and Longevity.

Crocco P et al.

Genes, 2019

31137904 (PubMed )
Supplement: genes-10-00403-s001.pdf

Pharmacogenetics of Membrane Transporters of Tacrolimus in Solid Organ Transplantation.

Tron C et al.

Clinical Pharmacokinetics, 2019

Genetic variability and population diversity of the human SLCO (OATP) transporter family.

Zhang B et al.

Pharmacological Research, 2019

Influence of the OATP Polymorphism on the Population Pharmacokinetics of Methotrexate in Chinese Patients.

Wang Z et al.

Current Drug Metabolism, 2019

Pharmacogenetics of hepatocellular carcinoma and cholangiocarcinoma.

Alonso-Peña M et al.

Cancer Drug Resistance (alhambra, Calif.), 2019

OATP1B3 (699G>A) and CYP2C9*2, *3 significantly influenced the transport and metabolism of glibenclamide and glipizide.

Yang F et al.

Scientific Reports, 2018

Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium.

Yee SW et al.

Clinical Pharmacology and Therapeutics, 2018

Association of Allelic Interaction of Single Nucleotide Polymorphisms of Influx and Efflux Transporters Genes With Nonhematologic Adverse Events of Docetaxel in Breast Cancer Patients.

Jabir RS et al.

Clinical Breast Cancer, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."