Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B3
Variant:p.N130D
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SLCO1B3

NM_019844.4:p.N130D

Associated Papers

Association of SLCO1B3 and SLCO1B1 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients.

Magadmi R et al.

Pharmaceuticals (basel, Switzerland), 2025

When the same treatment has different response: The role of pharmacogenomics in statin therapy.

Zheng E et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024

Genetic Diversity in Drug Transporters: Impact in African Populations.

Rajman I et al.

Clinical and Translational Science, 2020

Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokinetics.

Nie Y et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

Recent advance in the pharmacogenomics of human Solute Carrier Transporters (SLCs) in drug disposition.

Zhou F et al.

Advanced Drug Delivery Reviews, 2017

Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.

Chen S et al.

Drug Metabolism Reviews, 2016

More Power to OATP1B1: An Evaluation of Sample Size in Pharmacogenetic Studies Using a Rosuvastatin PBPK Model for Intestinal, Hepatic, and Renal Transporter-Mediated Clearances.

Emami Riedmaier A et al.

Journal of Clinical Pharmacology, 2016

Heritability of metoprolol and torsemide pharmacokinetics.

Matthaei J et al.

Clinical Pharmacology and Therapeutics, 2015

Pharmacogenetics of membrane transporters: a review of current approaches.

Sissung TM et al.

Methods in Molecular Biology (clifton, N.j.), 2014

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1.

Nies AT et al.

Genome Medicine, 2013

23311897 (PubMed )
Supplement: gm405-S1.PDF

OATP1B1 polymorphism as a determinant of erythromycin disposition.

Lancaster CS et al.

Clinical Pharmacology and Therapeutics, 2012

Influence of polymorphic OATP1B-type carriers on the disposition of docetaxel.

de Graan AJ et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2012

UGT1A1, SLCO1B1, and SLCO1B3 polymorphisms vs. neonatal hyperbilirubinemia: is there an association?

Alencastro de Azevedo L et al.

Pediatric Research, 2012

Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.

Fahrmayr C et al.

Drug Metabolism Reviews, 2010

The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.

Romaine SP et al.

The Pharmacogenomics Journal, 2010

Influence of the organic anion-transporting polypeptide 1B1 (OATP1B1) polymorphisms on irinotecan-pharmacokinetics and clinical outcome of patients with advanced non-small cell lung cancer.

Han JY et al.

Lung Cancer (amsterdam, Netherlands), 2008

The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members.

Seithel A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2008

Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.

Ieiri I et al.

Expert Opinion on Drug Metabolism & Toxicology, 2006

Pharmacogenomics of human OATP transporters.

König J et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2006

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans.

Tirona RG et al.

The Journal of Biological Chemistry, 2001

The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literature.

Anabtawi N et al.

Expert Opinion on Drug Metabolism & Toxicology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."