Varaico: Literature-Extracted Genetic Variants

Gene:SLCO2B1
Variant:p.P15S
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SLCO2B1

NM_007256.5:p.P15S

Associated Papers

Stoichiometric transport of estrone 3-sulfate among genetic variants of OATP1A2 and OATP2B1 and structural analysis by molecular dynamics simulation: Impairment of gating mechanism in the unstable inward-open conformation of OATP2B1 (Asp215Val) significantly suppress the transport activity.

Akiyoshi T et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025

Effects of polymorphisms of the SLCO2B1 transporter gene on the pharmacokinetics of montelukast in humans.

Kim KA et al.

Journal of Clinical Pharmacology, 2013

SLCO2B1 genetic polymorphisms in a Korean population: pyrosequencing analyses and comprehensive comparison with other populations.

Kim KA et al.

Molecular Biology Reports, 2013

SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren.

Tapaninen T et al.

Pharmacogenetics and Genomics, 2013

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1.

Nies AT et al.

Genome Medicine, 2013

23311897 (PubMed )
Supplement: gm405-S1.PDF
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."