Varaico: Literature-Extracted Genetic Variants

Gene:SLCO2B1
Variant:p.D215V
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SLCO2B1

NM_007256.5:p.D215V

Associated Papers

Stoichiometric transport of estrone 3-sulfate among genetic variants of OATP1A2 and OATP2B1 and structural analysis by molecular dynamics simulation: Impairment of gating mechanism in the unstable inward-open conformation of OATP2B1 (Asp215Val) significantly suppress the transport activity.

Akiyoshi T et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes: A GeT-RM Collaborative Project.

Pratt VM et al.

The Journal of Molecular Diagnostics : Jmd, 2016

Effects of polymorphisms of the SLCO2B1 transporter gene on the pharmacokinetics of montelukast in humans.

Kim KA et al.

Journal of Clinical Pharmacology, 2013

SLCO2B1 genetic polymorphisms in a Korean population: pyrosequencing analyses and comprehensive comparison with other populations.

Kim KA et al.

Molecular Biology Reports, 2013

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1.

Nies AT et al.

Genome Medicine, 2013

23311897 (PubMed )
Supplement: gm405-S1.PDF

Pharmacogenomics of organic anion-transporting polypeptides (OATP).

Tirona RG et al.

Advanced Drug Delivery Reviews, 2002

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