Varaico: Literature-Extracted Genetic Variants

Gene:SLCO2B1
Variant:p.T392I
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SLCO2B1

NM_007256.5:p.T392I

Associated Papers

In vitro characterization of SLCO2B1 genetic variants.

Sinokki A et al.

Journal of Pharmaceutical Sciences, 2025

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokinetics.

Nie Y et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

The Effect of Genetic Polymorphisms in SLCO2B1 on the Lipid-Lowering Efficacy of Rosuvastatin in Healthy Adults with Elevated Low-Density Lipoprotein.

Kim TE et al.

Basic & Clinical Pharmacology & Toxicology, 2017

Recent advance in the pharmacogenomics of human Solute Carrier Transporters (SLCs) in drug disposition.

Zhou F et al.

Advanced Drug Delivery Reviews, 2017

Comparison of genetic variations of the SLCO1B1, SLCO1B3, and SLCO2B1 genes among five ethnic groups.

Namgoong S et al.

Environmental Toxicology and Pharmacology, 2015

Effects of polymorphisms of the SLCO2B1 transporter gene on the pharmacokinetics of montelukast in humans.

Kim KA et al.

Journal of Clinical Pharmacology, 2013

SLCO2B1 genetic polymorphisms in a Korean population: pyrosequencing analyses and comprehensive comparison with other populations.

Kim KA et al.

Molecular Biology Reports, 2013

SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren.

Tapaninen T et al.

Pharmacogenetics and Genomics, 2013

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1.

Nies AT et al.

Genome Medicine, 2013

23311897 (PubMed )
Supplement: gm405-S1.PDF

Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms.

König J

Handbook of Experimental Pharmacology, 2011

Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomers.

Akamine Y et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2010

Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.

Fahrmayr C et al.

Drug Metabolism Reviews, 2010

The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members.

Seithel A et al.

Expert Opinion on Drug Metabolism & Toxicology, 2008

Implications of genetic polymorphisms in drug transporters for pharmacotherapy.

Kerb R

Cancer Letters, 2006

Pharmacogenomics of human OATP transporters.

König J et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2006

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).

Niemi M et al.

Pharmacogenetics, 2004

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis.

Nozawa T et al.

The Journal of Pharmacology and Experimental Therapeutics, 2002

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