Varaico: Literature-Extracted Genetic Variants

Gene:SLFN11
Variant:p.E669K
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SLFN11

NM_001376007.1:p.E669K

Associated Papers

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

Jo U et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."