Associated Papers
SLFN11 counteracts the RFWD3-PRIMPOL DNA damage tolerance axis to restrain gapped DNA synthesis in response to replication stress.
Coleman KE et al.
Nature Communications, 2025
The ribonuclease domain function is dispensable for SLFN11 to mediate cell fate decision during replication stress response.
Qi F et al.
Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2023
Structural, molecular, and functional insights into Schlafen proteins.
Jo U et al.
Experimental & Molecular Medicine, 2022
SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.
Okamoto Y et al.
Blood, 2021
SLFN11 Blocks Stressed Replication Forks Independently of ATR.
Murai J et al.
Molecular Cell, 2018
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
Mu Y et al.
Embo Reports, 2016
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