Associated Papers
RPA exhaustion activates SLFN11 to eliminate cells with heightened replication stress.
Stanage TH et al.
Nature Cell Biology, 2026
SLFN11 counteracts the RFWD3-PRIMPOL DNA damage tolerance axis to restrain gapped DNA synthesis in response to replication stress.
Coleman KE et al.
Nature Communications, 2025
Structural and functional characterization of human SLFN14.
Luo M et al.
Nucleic Acids Research, 2025
Phosphorylation-mediated conformational change regulates human SLFN11.
Kugler M et al.
Nature Communications, 2024
DNA damage induces p53-independent apoptosis through ribosome stalling.
Boon NJ et al.
Science (new York, N.y.), 2024
Structural and biochemical characterization of Schlafen11 N-terminal domain.
Hou P et al.
Nucleic Acids Research, 2023
Mechanistic understanding of human SLFN11.
Metzner FJ et al.
Nature Communications, 2022
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