Associated Papers
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer.
Fleming NI et al.
Cancer Research, 2013
Alterations in the Smad pathway in human cancers.
Samanta D et al.
Frontiers in Bioscience (landmark Edition), 2012
Cooperation between GATA4 and TGF-beta signaling regulates intestinal epithelial gene expression.
Belaguli NS et al.
American Journal of Physiology. Gastrointestinal and Liver Physiology, 2007
Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling.
Imoto S et al.
Febs Letters, 2005
Transforming growth factor-beta signaling is differentially inhibited by Smad2D450E and Smad3D407E.
Kondo M et al.
Cancer Science, 2004
Receptor-regulated Smads in TGF-beta signaling.
Liu F
Frontiers in Bioscience : a Journal and Virtual Library, 2003
Evidence for a role of Smad3 and Smad2 in stabilization of the tumor-derived mutant Smad2.Q407R.
Dumont E et al.
The Journal of Biological Chemistry, 2003
Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers.
Yanagisawa K et al.
Oncogene, 2000
Evidence that Smad2 is a tumor suppressor implicated in the control of cellular invasion.
Prunier C et al.
The Journal of Biological Chemistry, 1999
Dominant-negative Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus.
Hoodless PA et al.
Developmental Biology, 1999
TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.
Hata A et al.
Molecular Medicine Today, 1998
The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.
Lo RS et al.
The Embo Journal, 1998
Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes.
Liu F et al.
Genes & Development, 1997
MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma.
Eppert K et al.
Cell, 1996
Alterations in components of the TGF-beta superfamily signaling pathways in human cancer.
Levy L et al.
Cytokine & Growth Factor Reviews, 0
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