Varaico: Literature-Extracted Genetic Variants

Gene:SMAD2
Variant:p.D450H
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SMAD2

NM_005901.6:p.D450H

Associated Papers

Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.

Bourgeois B et al.

Science Signaling, 2013

Receptor-regulated Smads in TGF-beta signaling.

Liu F

Frontiers in Bioscience : a Journal and Virtual Library, 2003

Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling.

Wu JW et al.

Molecular Cell, 2001

Formation of a stable heterodimer between Smad2 and Smad4.

Wu JW et al.

The Journal of Biological Chemistry, 2001

TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.

Hata A et al.

Molecular Medicine Today, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."