Varaico: Literature-Extracted Genetic Variants

Gene:SMAD2
Variant:p.D300H
Back to variants list

SMAD2

NM_005901.6:p.D300H

Associated Papers

Common gene mutations in 103 authenticated colorectal cancer cell lines.

Kranjec C et al.

Oncogenesis, 2026

41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_10

Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.

Bourgeois B et al.

Science Signaling, 2013

Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription.

Ross S et al.

The Embo Journal, 2006

Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling.

Wu JW et al.

Molecular Cell, 2001

Formation of a stable heterodimer between Smad2 and Smad4.

Wu JW et al.

The Journal of Biological Chemistry, 2001

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."