Associated Papers
Oncogenic activation revealed by FGFR2 genetic alterations in intrahepatic cholangiocarcinomas.
Pu X et al.
Cell & Bioscience, 2023
37964396 (PubMed )
Supplement: 13578_2023_1156_MOESM12_ESM.xls › ____
Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types.
Boot A et al.
Genome Research, 2020
32661091 (PubMed )
Supplement: supp_gr.255620.119_Supplemental_Table_S2.xlsx › Sheet1
Pan-cancer whole-genome analyses of metastatic solid tumours.
Priestley P et al.
Nature, 2019
31645765 (PubMed )
Supplement: 41586_2019_1689_MOESM10_ESM.xlsx › Sheet1
Alterations in the Smad pathway in human cancers.
Samanta D et al.
Frontiers in Bioscience (landmark Edition), 2012
To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications.
Wrighton KH et al.
Cellular Signalling, 2008
Receptor-regulated Smads in TGF-beta signaling.
Liu F
Frontiers in Bioscience : a Journal and Virtual Library, 2003
Evidence for a role of Smad3 and Smad2 in stabilization of the tumor-derived mutant Smad2.Q407R.
Dumont E et al.
The Journal of Biological Chemistry, 2003
Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4.
Morén A et al.
Oncogene, 2000
Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway.
Xu J et al.
Proceedings of the National Academy of Sciences of the United States of America, 2000
Expression and mutational analysis of the MADR2/Smad2 gene in human prostate cancer.
Latil A et al.
The Prostate, 1999
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling.
Shi Y et al.
Cell, 1998
Mutational analysis of the tumor suppressor Smad2 in acute lymphoid and myeloid leukemia.
Wieser R et al.
Leukemia, 1998
TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.
Hata A et al.
Molecular Medicine Today, 1998
MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma.
Eppert K et al.
Cell, 1996
Alterations in components of the TGF-beta superfamily signaling pathways in human cancer.
Levy L et al.
Cytokine & Growth Factor Reviews, 0
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