Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.L43S
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SMAD4

NM_005359.6:p.L43S

Associated Papers

Structural determinants of Smad function in TGF-β signaling.

Macias MJ et al.

Trends in Biochemical Sciences, 2015

Phospho-control of TGF-beta superfamily signaling.

Wrighton KH et al.

Cell Research, 2009

To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications.

Wrighton KH et al.

Cellular Signalling, 2008

Activation of hypoxia-induced transcription in normoxia.

Hägg M et al.

Experimental Cell Research, 2005

Two somatic biallelic lesions within and near SMAD4 in a human breast cancer cell line.

Jakob J et al.

Genes, Chromosomes & Cancer, 2005

Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation.

Izzi L et al.

Oncogene, 2004

Regulation of large-scale chromatin unfolding by Smad4.

Yan J et al.

Biochemical and Biophysical Research Communications, 2004

Differential ubiquitination defines the functional status of the tumor suppressor Smad4.

Morén A et al.

The Journal of Biological Chemistry, 2003

Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4.

Morén A et al.

Oncogene, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."