Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.G86V
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SMAD4

NM_005359.6:p.G86V

Associated Papers

Circulating Tumour DNA Sequencing Identifies a Genetic Resistance-Gap in Colorectal Cancers with Acquired Resistance to EGFR-Antibodies and Chemotherapy.

Knebel FH et al.

Cancers, 2020

33322618 (PubMed )
Supplement: cancers-12-03736-s001.pdf

SMAD4 alteration associates with invasive-front pathological markers and poor prognosis in colorectal cancer.

Oyanagi H et al.

Histopathology, 2019

Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine.

Hou H et al.

Oncotarget, 2017

29285234 (PubMed )
Supplement: oncotarget-08-105072-s002.xlsx › Data

Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers.

Hirshfield KM et al.

The Oncologist, 2016

27566247 (PubMed )
Supplement: supp_the2016-0049_Supplemental_Tables.pdf

Missense mutations of MADH4: characterization of the mutational hot spot and functional consequences in human tumors.

Iacobuzio-Donahue CA et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."