Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.K113R
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SMAD4

NM_005359.6:p.K113R

Associated Papers

Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2.

Hsu WL et al.

Bmc Biology, 2017

Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4.

Chang CC et al.

The Journal of Biological Chemistry, 2005

Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1.

Liang M et al.

The Journal of Biological Chemistry, 2004

Repression of Smad4 transcriptional activity by SUMO modification.

Long J et al.

The Biochemical Journal, 2004

SUMO-1/Ubc9 promotes nuclear accumulation and metabolic stability of tumor suppressor Smad4.

Lin X et al.

The Journal of Biological Chemistry, 2003

Sumoylation of Smad4, the common Smad mediator of transforming growth factor-beta family signaling.

Lee PS et al.

The Journal of Biological Chemistry, 2003

Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4.

Lin X et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."