Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.C115R
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SMAD4

NM_005359.6:p.C115R

Associated Papers

DNA-binding domain mutations in SMAD genes yield dominant-negative proteins or a neomorphic protein that can activate WG target genes in Drosophila.

Takaesu NT et al.

Development (cambridge, England), 2005

Tumor-derived C-terminal mutations of Smad4 with decreased DNA binding activity and enhanced intramolecular interaction.

Kuang C et al.

Oncogene, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."