Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.C324Y
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SMAD4

NM_005359.6:p.C324Y

Associated Papers

Common gene mutations in 103 authenticated colorectal cancer cell lines.

Kranjec C et al.

Oncogenesis, 2026

41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_10

A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancer.

Xiao J et al.

Bmc Cancer, 2021

33726687 (PubMed )
Supplement: 12885_2021_7942_MOESM3_ESM.xlsx › Table_S2

Roles of Smads Family and Alternative Splicing Variants of Smad4 in Different Cancers.

Ullah I et al.

Journal of Cancer, 2018

SMAD4 gene promoter mutations in patients with thyroid tumors.

Nikolic A et al.

Experimental and Molecular Pathology, 2015

Effects of the Smad4 C324Y mutation on thyroid cell proliferation.

D'Inzeo S et al.

International Journal of Oncology, 2013

A novel human Smad4 mutation is involved in papillary thyroid carcinoma progression.

D'Inzeo S et al.

Endocrine-related Cancer, 2012

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

A complex pattern of mutations and abnormal splicing of Smad4 is present in thyroid tumours.

Lazzereschi D et al.

Oncogene, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."