Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.Y353C
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SMAD4

NM_005359.6:p.Y353C

Associated Papers

Novel Methodology for the Design of Personalized Cancer Vaccine Targeting Neoantigens: Application to Pancreatic Ductal Adenocarcinoma.

Savsani K et al.

Diseases (basel, Switzerland), 2024

Targeted next-generation sequencing of 491 lung cancers in clinical practice: Implications for future detection strategy and targeted therapy.

Liu XD et al.

Heliyon, 2024

38496837 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Significance of TP53, CDKN2A, SMAD4 and KRAS in Pancreatic Cancer.

Stefanoudakis D et al.

Current Issues in Molecular Biology, 2024

Juvenile polyposis diagnosed with an integrated histological, immunohistochemical and molecular approach identifying new SMAD4 pathogenic variants.

Mafficini A et al.

Familial Cancer, 2022

Next-generation sequencing-based identification of EGFR and NOTCH2 complementary mutations in non-small cell lung cancer.

Niu L et al.

Oncology Letters, 2021

Frequent post-operative monitoring of colorectal cancer using individualised ctDNA validated by multiregional molecular profiling.

Yaegashi M et al.

British Journal of Cancer, 2021

33658639 (PubMed )
Supplement: 41416_2021_1266_MOESM2_ESM.xlsx › Date_file_S1

Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma.

Winter H et al.

Cancers, 2019

31795195 (PubMed )
Supplement: cancers-11-01895-s001.zip › ICC_ctDNA_Cancers_Supplementary_Table_5._50_cancer_gene_panel_information.xlsx › cms_106003

SMAD4 Y353C promotes the progression of PDAC.

Wang Z et al.

Bmc Cancer, 2019

Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers.

Hänninen UA et al.

British Journal of Cancer, 2019

30894686 (PubMed )
Supplement: 41416_2019_427_MOESM4_ESM.xlsx › Sheet1

Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Koyama T et al.

Bmc Cancer, 2019

30709382 (PubMed )
Supplement: 12885_2019_5313_MOESM2_ESM.xlsx › supplementary_2_filtered

Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.

Ross JS et al.

Cancer, 2018

29338072 (PubMed )
Supplement: CNCR-124-1358-s002.xlsx › Colon

Analytic validation and real-time clinical application of an amplicon-based targeted gene panel for advanced cancer.

Wing MR et al.

Oncotarget, 2017

29100271 (PubMed )
Supplement: oncotarget-08-75822-s008.xlsx › S7._167_patients

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

Homozygous Germline APC p.I1307K Variants: A Case Series.

Rosenblum A et al.

Case Reports in Oncology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."