Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.D355N
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SMAD4

NM_005359.6:p.D355N

Associated Papers

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Fragoza R et al.

Nature Communications, 2019

31515488 (PubMed )
Supplement: 41467_2019_11959_MOESM7_ESM.xlsx › SD3_-_COSMIC_Mutations

Three dimensional primary cultures for selecting human breast cancers that are sensitive to the anti-tumor activity of ipatasertib or taselisib in combination with anti-microtubule cytotoxic drugs.

Orditura M et al.

Breast (edinburgh, Scotland), 2018

Cell-Free DNA and Neuromediators in Detecting Aggressive Variant Prostate Cancer.

von Hardenberg J et al.

Oncology Research and Treatment, 2018

Detection of dysregulated protein-association networks by high-throughput proteomics predicts cancer vulnerabilities.

Lapek JD et al.

Nature Biotechnology, 2017

28892078 (PubMed )
Supplement: NIHMS73743-supplement-Supplementary_tables.zip › Supplementary_Table_10_Proteins_with_Nonsense_Mutations_26_Breast_Cancer_Cell_Lines.xlsx › Sheet2

Ultra-deep targeted sequencing of advanced oral squamous cell carcinoma identifies a mutation-based prognostic gene signature.

Chen SJ et al.

Oncotarget, 2015

25980437 (PubMed )
Supplement: oncotarget-06-18066-s004.xlsx › Sheet1

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.

Dalgliesh GL et al.

Nature, 2010

20054297 (PubMed )
Supplement: NIHMS28099-supplement-4.xls › Sheet1
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."