Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.V465M
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SMAD4

NM_005359.6:p.V465M

Associated Papers

The targeted next-generation sequence revealed SMAD4, AKT1, and TP53 mutations from circulating cell-free DNA of breast cancer and its effect on protein structure - A computational approach.

Balasundaram A et al.

Journal of Biomolecular Structure & Dynamics, 2023

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells.

Manic G et al.

Gut, 2018

28389531 (PubMed )
Supplement: gutjnl-2016-312623supp002.pdf

Germline mutations in SMAD4 disrupt bone morphogenetic protein signaling.

Carr JC et al.

The Journal of Surgical Research, 2012

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