Varaico: Literature-Extracted Genetic Variants

Gene:SMAD4
Variant:p.G508S
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SMAD4

NM_005359.6:p.G508S

Associated Papers

Targeted Next-Generation Sequencing-Based Multiple Gene Mutation Profiling of Patients with Rectal Adenocarcinoma Receiving or Not Receiving Neoadjuvant Chemoradiotherapy.

Chang YK et al.

International Journal of Molecular Sciences, 2022

36142267 (PubMed )
Supplement: ijms-23-10353-s001.zip › ijms-1910530-supplementary.pdf

A novel SMAD4 gene mutation in seminoma germ cell tumors.

Bouras M et al.

Cancer Research, 2000

The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain.

de Caestecker MP et al.

The Journal of Biological Chemistry, 2000

TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.

Hata A et al.

Molecular Medicine Today, 1998

The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

Lo RS et al.

The Embo Journal, 1998

Characterization of functional domains within Smad4/DPC4.

de Caestecker MP et al.

The Journal of Biological Chemistry, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."