Associated Papers
Development of a functional assay for the characterisation of SMAD4 variants from the French haemorrhagic hereditary telangiectasia cohort.
Despas L et al.
Journal of Medical Genetics, 2025
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.
Jbara A et al.
Nature, 2023
PRMT5 methylating SMAD4 activates TGF-β signaling and promotes colorectal cancer metastasis.
Liu A et al.
Oncogene, 2023
Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.
Montes-Rodríguez IM et al.
Cancer Medicine, 2023
Spatially interacting phosphorylation sites and mutations in cancer.
Huang KL et al.
Nature Communications, 2021
Validation and clinical application of a targeted next-generation sequencing gene panel for solid and hematologic malignancies.
Prieto-Potin I et al.
Peerj, 2020
The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.
Punta M et al.
Frontiers in Immunology, 2020
Biophysical simulations and structure-based modeling of residue interaction networks in the tumor suppressor proteins reveal functional role of cancer mutation hotspots in molecular communication.
Verkhivker GM
Biochimica Et Biophysica Acta. General Subjects, 2019
Contribution of allelic imbalance to colorectal cancer.
Palin K et al.
Nature Communications, 2018
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer.
Fleming NI et al.
Cancer Research, 2013
Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling.
Imoto S et al.
Febs Letters, 2005
Regulation of large-scale chromatin unfolding by Smad4.
Yan J et al.
Biochemical and Biophysical Research Communications, 2004
Receptor-regulated Smads in TGF-beta signaling.
Liu F
Frontiers in Bioscience : a Journal and Virtual Library, 2003
Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability.
Maurice D et al.
The Journal of Biological Chemistry, 2001
Distinct oligomeric states of SMAD proteins in the transforming growth factor-beta pathway.
Jayaraman L et al.
The Journal of Biological Chemistry, 2000
Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal.
Watanabe M et al.
Embo Reports, 2000
Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers.
Yanagisawa K et al.
Oncogene, 2000