Associated Papers
Cell type-specific functions of the PBAF chromatin-remodeling complex in neuronal diversification.
Osuma A et al.
Nature Communications, 2025
Targeting ALDH16A1 mediated thioredoxin lysosomal degradation to enhance ferroptosis susceptibility in SMARCA4-deficient NSCLC.
Bi G et al.
Nature Communications, 2025
A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform.
Jain SU et al.
Biorxiv : the Preprint Server for Biology, 2025
MYC Regulates a DNA Repair Gene Expression Program in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.
Evans JR et al.
Cancers, 2025
TP53 missense mutation reveals gain-of-function properties in small-sized KRAS transformed pancreatic ductal adenocarcinoma.
Zhou Y et al.
Journal of Translational Medicine, 2023
A disordered region controls cBAF activity via condensation and partner recruitment.
Patil A et al.
Cell, 2023
Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss.
Zhu X et al.
Nature Communications, 2023
The Interaction of SWI/SNF with the Ribosome Regulates Translation and Confers Sensitivity to Translation Pathway Inhibitors in Cancers with Complex Perturbations.
Ulicna L et al.
Cancer Research, 2022
On the Interaction Between SMARCAL1 and BRG1.
Bisht D et al.
Frontiers in Cell and Developmental Biology, 2022
Brg1 mutation alters oxidative stress responses in glioblastoma.
Gowda P et al.
Neurochemistry International, 2021
The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription-replication conflicts.
Bayona-Feliu A et al.
Nature Genetics, 2021
Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism.
Orlando KA et al.
Elife, 2020
Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients.
Fernando TM et al.
Nature Communications, 2020
The Discovery of SWI/SNF Chromatin Remodeling Activity as a Novel and Targetable Dependency in Uveal Melanoma.
Rago F et al.
Molecular Cancer Therapeutics, 2020
A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites.
Chen Y et al.
Nucleic Acids Research, 2019
Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.
Gao F et al.
Molecular Cell, 2019
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting.
Pan J et al.
Nature Genetics, 2019
Elucidation of the functional roles of the Q and I motifs in the human chromatin-remodeling enzyme BRG1.
Hoffmeister H et al.
The Journal of Biological Chemistry, 2019
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.
Hodges HC et al.
Nature Structural & Molecular Biology, 2018
Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin.
Stanton BZ et al.
Nature Genetics, 2017
BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.
Wang H et al.
Molecular Cell, 2016
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability.
Husain A et al.
Nature Communications, 2016
Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.
Smith-Roe SL et al.
Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2013
Participation of Brahma-related gene 1 (BRG1)-associated factor 57 and BRG1-containing chromatin remodeling complexes in thyroid hormone-dependent gene activation during vertebrate development.
Heimeier RA et al.
Molecular Endocrinology (baltimore, Md.), 2008
A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription.
Huang ZQ et al.
The Embo Journal, 2003