Varaico: Literature-Extracted Genetic Variants

Gene:SMC3
Variant:p.K113Q
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SMC3

NM_005445.4:p.K113Q

Associated Papers

Cohesin Acetylation and ATPase Activity Control Cohesion and Loop Architecture through Distinct Mechanisms.

Costantino L et al.

Biorxiv : the Preprint Server for Biology, 2025

41280095 (PubMed )
Supplement: NIHPP2025.10.30.685539v1-supplement-1.pdf

Conformational dynamics of cohesin/Scc2 loading complex are regulated by Smc3 acetylation and ATP binding.

Kaushik A et al.

Nature Communications, 2023

A model for Scc2p stimulation of cohesin's ATPase and its inhibition by acetylation of Smc3p.

Boardman K et al.

Genes & Development, 2023

ESCO1/2's roles in chromosome structure and interphase chromatin organization.

Kawasumi R et al.

Genes & Development, 2017

A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase.

Guacci V et al.

Molecular Biology of the Cell, 2015

Cohesin codes - interpreting chromatin architecture and the many facets of cohesin function.

Rudra S et al.

Journal of Cell Science, 2013

Cohesin-independent segregation of sister chromatids in budding yeast.

Guacci V et al.

Molecular Biology of the Cell, 2012

Eco1 is important for DNA damage repair in S. cerevisiae.

Lu S et al.

Cell Cycle (georgetown, Tex.), 2010

A molecular determinant for the establishment of sister chromatid cohesion.

Unal E et al.

Science (new York, N.y.), 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."