Varaico: Literature-Extracted Genetic Variants

Gene:SMC3
Variant:p.K113R
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SMC3

NM_005445.4:p.K113R

Associated Papers

Cohesin Acetylation and ATPase Activity Control Cohesion and Loop Architecture through Distinct Mechanisms.

Costantino L et al.

Biorxiv : the Preprint Server for Biology, 2025

41280095 (PubMed )
Supplement: NIHPP2025.10.30.685539v1-supplement-1.pdf

A model for Scc2p stimulation of cohesin's ATPase and its inhibition by acetylation of Smc3p.

Boardman K et al.

Genes & Development, 2023

A role for the Smc3 hinge domain in the maintenance of sister chromatid cohesion.

Robison B et al.

Molecular Biology of the Cell, 2018

The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering.

Çamdere G et al.

Elife, 2015

Interallelic complementation provides functional evidence for cohesin-cohesin interactions on DNA.

Eng T et al.

Molecular Biology of the Cell, 2015

A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase.

Guacci V et al.

Molecular Biology of the Cell, 2015

Cohesin codes - interpreting chromatin architecture and the many facets of cohesin function.

Rudra S et al.

Journal of Cell Science, 2013

Cohesin-independent segregation of sister chromatids in budding yeast.

Guacci V et al.

Molecular Biology of the Cell, 2012

Genetic evidence that the acetylation of the Smc3p subunit of cohesin modulates its ATP-bound state to promote cohesion establishment in Saccharomyces cerevisiae.

Heidinger-Pauli JM et al.

Genetics, 2010

Both interaction surfaces within cohesin's hinge domain are essential for its stable chromosomal association.

Mishra A et al.

Current Biology : Cb, 2010

Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity.

Rowland BD et al.

Molecular Cell, 2009

Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion.

Rolef Ben-Shahar T et al.

Science (new York, N.y.), 2008

A molecular determinant for the establishment of sister chromatid cohesion.

Unal E et al.

Science (new York, N.y.), 2008

Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast.

Zhang J et al.

Molecular Cell, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."