Varaico: Literature-Extracted Genetic Variants

Gene:SMO
Variant:p.F460L
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SMO

NM_005631.5:p.F460L

Associated Papers

Towards Precision Oncology: The Role of Smoothened and Its Variants in Cancer.

Nicheperovich A et al.

Journal of Personalized Medicine, 2022

The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Punta M et al.

Frontiers in Immunology, 2020

33133066 (PubMed )
Supplement: Table_1.xlsx › Resistance-no-BCR-ABL1

A computational study of hedgehog signalling involved in basal cell carcinoma reveals the potential and limitation of combination therapy.

Buetti-Dinh A et al.

Bmc Cancer, 2018

Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond.

Bakshi A et al.

Molecular Carcinogenesis, 2017

Smoothened variants explain the majority of drug resistance in basal cell carcinoma.

Atwood SX et al.

Cancer Cell, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."