Associated Papers
The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function.
Koganti P et al.
Cellular and Molecular Life Sciences : Cmls, 2022
SMURF2-mediated ubiquitin signaling plays an essential role in the regulation of PARP1 PARylating activity, molecular interactions, and functions in mammalian cells.
Ilić N et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2021
Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer.
Emanuelli A et al.
Cancers, 2019
Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin.
Borroni AP et al.
Aging Cell, 2018
Smurfs in Protein Homeostasis, Signaling, and Cancer.
Koganti P et al.
Frontiers in Oncology, 2018
Smurf2-Mediated Stabilization of DNA Topoisomerase IIα Controls Genomic Integrity.
Emanuelli A et al.
Cancer Research, 2017
HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.
ZeRuth GT et al.
Plos One, 2015
The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2).
Kim S et al.
The Journal of Biological Chemistry, 2010
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