Varaico: Literature-Extracted Genetic Variants

Gene:SNCA
Variant:p.S129C
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SNCA

NM_000345.4:p.S129C

Associated Papers

Early-Onset Parkinson Mutation Remodels Monomer-Fibril Interactions to Allosterically Amplify Synuclein's Amyloid Cascade.

Huang J et al.

Jacs Au, 2023

Intramolecular interaction kinetically regulates fibril formation by human and mouse α-synuclein.

Ohgita T et al.

Scientific Reports, 2023

A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function.

Doherty CPA et al.

Nature Structural & Molecular Biology, 2020

Alpha-synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains.

Stöckl M et al.

Journal of Molecular Biology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."