Varaico: Literature-Extracted Genetic Variants

Gene:SNCA
Variant:p.A89P
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SNCA

NM_000345.4:p.A89P

Associated Papers

The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.

Hallacli E et al.

Cell, 2022

Membrane Binding of α-Synuclein Stimulates Expansion of SNARE-Dependent Fusion Pore.

Khounlo R et al.

Frontiers in Cell and Developmental Biology, 2021

Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities.

Burré J et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2012

Aggregation-defective alpha-synuclein mutants inhibit the fibrillation of Parkinson's disease-linked alpha-synuclein variants.

Koo HJ et al.

Biochemical and Biophysical Research Communications, 2009

Sequence determinants regulating fibrillation of human alpha-synuclein.

Koo HJ et al.

Biochemical and Biophysical Research Communications, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."