Associated Papers
Defining essential charged residues in fibril formation of a lysosomal derived N-terminal α-synuclein truncation.
McGlinchey RP et al.
Nature Communications, 2025
Structurally targeted mutagenesis identifies key residues supporting α -synuclein misfolding in multiple system atrophy.
Reis PM et al.
Biorxiv : the Preprint Server for Biology, 2024
39026799 (PubMed )
Supplement: media-1.pdf
Protein arginylation targets alpha synuclein, facilitates normal brain health, and prevents neurodegeneration.
Wang J et al.
Scientific Reports, 2017
Residue Glu83 plays a major role in negatively regulating alpha-synuclein amyloid formation.
Waxman EA et al.
Biochemical and Biophysical Research Communications, 2010
Characterization of hydrophobic residue requirements for alpha-synuclein fibrillization.
Waxman EA et al.
Biochemistry, 2009
Inhibition of alpha-synuclein fibrillization by dopamine is mediated by interactions with five C-terminal residues and with E83 in the NAC region.
Herrera FE et al.
Plos One, 2008
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