Varaico: Literature-Extracted Genetic Variants

Gene:SNCA
Variant:p.T72P
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SNCA

NM_000345.4:p.T72P

Associated Papers

Polymorphism in alpha-synuclein oligomers and its implications in toxicity under disease conditions.

Yoo JM et al.

Frontiers in Molecular Biosciences, 2022

Perry Disease: Concept of a New Disease and Clinical Diagnostic Criteria.

Tsuboi Y et al.

Journal of Movement Disorders, 2021

Effects of Mutations on the Reconfiguration Rate of α-Synuclein.

Acharya S et al.

The Journal of Physical Chemistry. B, 2015

O-GlcNAc modification prevents peptide-dependent acceleration of α-synuclein aggregation.

Marotta NP et al.

Chembiochem : a European Journal of Chemical Biology, 2012

A novel, high-efficiency cellular model of fibrillar alpha-synuclein inclusions and the examination of mutations that inhibit amyloid formation.

Waxman EA et al.

Journal of Neurochemistry, 2010

beta-Sheet-breaking peptides inhibit the fibrillation of human alpha-synuclein.

Kim YS et al.

Biochemical and Biophysical Research Communications, 2009

Aggregation-defective alpha-synuclein mutants inhibit the fibrillation of Parkinson's disease-linked alpha-synuclein variants.

Koo HJ et al.

Biochemical and Biophysical Research Communications, 2009

Sequence determinants regulating fibrillation of human alpha-synuclein.

Koo HJ et al.

Biochemical and Biophysical Research Communications, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."