Varaico: Literature-Extracted Genetic Variants

Gene:SNCA
Variant:p.V66D
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SNCA

NM_000345.4:p.V66D

Associated Papers

Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson's disease.

Yan S et al.

Cell Reports. Medicine, 2025

Aggregation-resistant alpha-synuclein tetramers are reduced in the blood of Parkinson's patients.

de Boni L et al.

Embo Molecular Medicine, 2024

Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes.

Nuber S et al.

Npj Parkinson's Disease, 2024

Pathogenic Mechanisms of Cytosolic and Membrane-Enriched α-Synuclein Converge on Fatty Acid Homeostasis.

Tripathi A et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."