Varaico: Literature-Extracted Genetic Variants

Gene:SNCA
Variant:p.K45E
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SNCA

NM_000345.4:p.K45E

Associated Papers

Insights into the Molecular Mechanisms of Alzheimer's and Parkinson's Diseases with Molecular Simulations: Understanding the Roles of Artificial and Pathological Missense Mutations in Intrinsically Disordered Proteins Related to Pathology.

Coskuner-Weber O et al.

International Journal of Molecular Sciences, 2018

Molecular determinants of α-synuclein mutants' oligomerization and membrane interactions.

Tsigelny IF et al.

Acs Chemical Neuroscience, 2015

Aggregation-defective alpha-synuclein mutants inhibit the fibrillation of Parkinson's disease-linked alpha-synuclein variants.

Koo HJ et al.

Biochemical and Biophysical Research Communications, 2009

Sequence determinants regulating fibrillation of human alpha-synuclein.

Koo HJ et al.

Biochemical and Biophysical Research Communications, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."