Associated Papers
Is synuclein aggregation a derived or ancestral trait? Ancestral sequence reconstruction uncovers stepwise evolution of synuclein aggregation.
Sam A et al.
Biorxiv : the Preprint Server for Biology, 2025
C-terminal truncation modulates α-Synuclein's cytotoxicity and aggregation by promoting the interactions with membrane and chaperone.
Zhang C et al.
Communications Biology, 2022
Wild-Type α-Synuclein and Variants Occur in Different Disordered Dimers and Pre-Fibrillar Conformations in Early Stage of Aggregation.
Guzzo A et al.
Frontiers in Molecular Biosciences, 2022
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation.
Angelova PR et al.
Cell Death and Differentiation, 2020
A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function.
Doherty CPA et al.
Nature Structural & Molecular Biology, 2020
Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis.
Hughes CD et al.
Acta Neuropathologica, 2019
Site-specific structural dynamics of α-Synuclein revealed by time-resolved fluorescence spectroscopy: a review.
Sahay S et al.
Methods and Applications in Fluorescence, 2016
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids.
Horrocks MH et al.
Acs Chemical Neuroscience, 2016
Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants.
Tosatto L et al.
Scientific Reports, 2015
26582456 (PubMed )
Supplement: srep16696-s1.pdf
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