Varaico: Literature-Extracted Genetic Variants

Gene:SNCA
Variant:p.K23R
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SNCA

NM_000345.4:p.K23R

Associated Papers

Listerin promotes α-synuclein degradation to alleviate Parkinson's disease through the ESCRT pathway.

Qin F et al.

Science Advances, 2025

Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation.

Zenko D et al.

Science Advances, 2023

The mutation spectrum of Parkinson-disease-related genes in early-onset Parkinson's disease in ethnic Chinese.

Chen YP et al.

European Journal of Neurology, 2022

35861376 (PubMed )
Supplement: supplement_1.pdf

β-Turn exchanges in the α-synuclein segment 44-TKEG-47 reveal high sequence fidelity requirements of amyloid fibril elongation.

Agerschou ED et al.

Biophysical Chemistry, 2021

Mutation Analysis of DNAJC Family for Early-Onset Parkinson's Disease in a Chinese Cohort.

Li C et al.

Movement Disorders : Official Journal of the Movement Disorder Society, 2020

Sumoylation inhibits alpha-synuclein aggregation and toxicity.

Krumova P et al.

The Journal of Cell Biology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."