Associated Papers
Structural Insights into the Dynamics of Water in SOD1 Catalysis and Drug Interactions.
Yapici I et al.
International Journal of Molecular Sciences, 2025
Landscapes of missense variant impact for human superoxide dismutase 1.
Axakova A et al.
Biorxiv : the Preprint Server for Biology, 2025
Fundamental Neurochemistry Review: Copper availability as a potential therapeutic target in progressive supranuclear palsy: Insight from other neurodegenerative diseases.
Billings JL et al.
Journal of Neurochemistry, 2023
Molecular dynamics of a far positioned SOD1 mutant V14M reveals pathogenic misfolding behavior.
Tompa DR et al.
Journal of Biomolecular Structure & Dynamics, 2018
Lipid-associated aggregate formation of superoxide dismutase-1 is initiated by membrane-targeting loops.
Chng CP et al.
Proteins, 2014
Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants.
Das A et al.
Journal of Molecular Biology, 2013
SOD1 exhibits allosteric frustration to facilitate metal binding affinity.
Das A et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013
Structural switching of Cu,Zn-superoxide dismutases at loop VI: insights from the crystal structure of 2-mercaptoethanol-modified enzyme.
Ihara K et al.
Bioscience Reports, 2012
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation.
Pesaresi MG et al.
Human Molecular Genetics, 2011
A novel T137A SOD1 mutation in an Italian family with two subjects affected by amyotrophic lateral sclerosis.
Visani M et al.
Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2011
FALS mutations in Cu, Zn superoxide dismutase destabilize the dimer and increase dimer dissociation propensity: a large-scale thermodynamic analysis.
Khare SD et al.
Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis, 2006
Mutant SOD1 instability: implications for toxicity in amyotrophic lateral sclerosis.
Tiwari A et al.
Neuro-degenerative Diseases, 2005
The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status.
Arnesano F et al.
The Journal of Biological Chemistry, 2004
Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human Cu,Zn superoxide dismutase.
Fisher CL et al.
Proteins, 1997
Synthesis and characterization of a monomeric mutant Cu/Zn superoxide dismutase with partially reconstituted enzymic activity.
Banci L et al.
European Journal of Biochemistry, 1995