Varaico: Literature-Extracted Genetic Variants

Gene:SOD2
Variant:p.K68Q
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SOD2

NM_000636.4:p.K68Q

Associated Papers

Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.

Coelho DR et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

The structure-function relationships and physiological roles of MnSOD mutants.

Bonetta Valentino R

Bioscience Reports, 2022

Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site.

Lu J et al.

Free Radical Biology & Medicine, 2015

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS.

Chen Y et al.

Embo Reports, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."