Varaico: Literature-Extracted Genetic Variants

Gene:SOSTDC1
Variant:p.G74C
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SOSTDC1

NM_015464.3:p.G74C

Associated Papers

Ground-State Destabilization by Active-Site Hydrophobicity Controls the Selectivity of a Cofactor-Free Decarboxylase.

Biler M et al.

Journal of the American Chemical Society, 2020

33180505 (PubMed )
Supplement: ja0c10701_si_001.pdf

Structural basis for inverting the enantioselectivity of arylmalonate decarboxylase revealed by the structural analysis of the Gly74Cys/Cys188Ser mutant in the liganded form.

Obata R et al.

Biochemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."