Varaico: Literature-Extracted Genetic Variants

Gene:SOX9
Variant:p.T236A
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SOX9

NM_000346.4:p.T236A

Associated Papers

KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.

Shao N et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2020

33173725 (PubMed )
Supplement: ADVS-7-2001018-s001.pdf

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.

Suryo Rahmanto A et al.

The Embo Journal, 2016

SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.

Hong X et al.

Nucleic Acids Research, 2016

27566146 (PubMed )
Supplement: supp_gkw748_nar-00891-d-2016-File009.pdf
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