Associated Papers
Missense variants weakening a SOX9 phosphodegron linked to odontogenesis defects, scoliosis, and other skeletal features.
Ettaki I et al.
Hgg Advances, 2025
KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.
Shao N et al.
Advanced Science (weinheim, Baden-wurttemberg, Germany), 2020
33173725 (PubMed )
Supplement: ADVS-7-2001018-s001.pdf
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
Suryo Rahmanto A et al.
The Embo Journal, 2016
SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.
Hong X et al.
Nucleic Acids Research, 2016
27566146 (PubMed )
Supplement: supp_gkw748_nar-00891-d-2016-File009.pdf
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