Varaico: Literature-Extracted Genetic Variants

Gene:SP1
Variant:p.S101A
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SP1

NM_138473.3:p.S101A

Associated Papers

DNA damage-induced degradation of Sp1 promotes cellular senescence.

Swift ML et al.

Geroscience, 2022

DNA damage-induced sumoylation of Sp1 induces its interaction with RNF4 and degradation in S phase to remove 53BP1 from DSBs and permit HR.

Swift ML et al.

Dna Repair, 2022

Sp1-dependent recruitment of the histone acetylase p300 to DSBs facilitates chromatin remodeling and recruitment of the NHEJ repair factor Ku70.

Swift ML et al.

Dna Repair, 2021

Sp1 phosphorylation by ATM downregulates BER and promotes cell elimination in response to persistent DNA damage.

Fletcher SC et al.

Nucleic Acids Research, 2018

Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites.

Iwahori S et al.

Cellular Signalling, 2008

Phosphorylation of Sp1 in response to DNA damage by ataxia telangiectasia-mutated kinase.

Olofsson BA et al.

Molecular Cancer Research : Mcr, 2007

Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein.

Iwahori S et al.

Journal of Virology, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."