Varaico: Literature-Extracted Genetic Variants

Gene:SPOP
Variant:p.F133S
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SPOP

NM_001007228.2:p.F133S

Associated Papers

Deep Sequencing Reveals Novel Mutations in Androgen Receptor-Related Genes in Prostate Cancer.

Pedroza-Torres A et al.

International Journal of Molecular Sciences, 2025

SPOP and MMR/MSI alterations in prostate cancer: relationship with PD-L1, TILs and AR expression.

Fiorentino V et al.

Pathologica, 2025

Generation of prostate cancer assembloids modeling the patient-specific tumor microenvironment.

Lee J et al.

Plos Genetics, 2025

40163511 (PubMed )
Supplement: pgen.1011652.s005.xlsx › organoid_somatic_variants

Genomic profiling and clinical utility of circulating tumor DNA in metastatic prostate cancer: SCRUM-Japan MONSTAR SCREEN project.

Shiota M et al.

Bjc Reports, 2024

39516321 (PubMed )
Supplement: 44276_2024_49_MOESM4_ESM.xlsx › supplementary_table_2

Opposing Roles of SPOP Mutations in Human Prostate and Endometrial Cancers.

Cavalcante L et al.

Jco Precision Oncology, 2023

Molecular features and race-associated outcomes of SPOP-mutant metastatic castration-resistant prostate cancer.

Stangl A et al.

The Prostate, 2023

Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

White JA et al.

Cancer Research Communications, 2022

36922933 (PubMed )
Supplement: crc-22-0136-s01.xlsx › ST3_Known_Somatic_Variants

The evolving landscape of prostate cancer somatic mutations.

Cotter K et al.

The Prostate, 2022

2-kupl: mapping-free variant detection from DNA-seq data of matched samples.

Wang Y et al.

Bmc Bioinformatics, 2021

34090332 (PubMed )
Supplement: 12859_2021_4185_MOESM3_ESM.xlsx › Table_S2

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.

Bernasocchi T et al.

Nature Communications, 2021

Factors that influence the androgen receptor cistrome in benign and malignant prostate cells.

Copeland BT et al.

Molecular Oncology, 2019

Analysis of error profiles in deep next-generation sequencing data.

Ma X et al.

Genome Biology, 2019

30867008 (PubMed )
Supplement: 13059_2019_1659_MOESM1_ESM.xlsx › S3_b

SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG.

Shoag J et al.

The Journal of Clinical Investigation, 2018

29202479 (PubMed )
Supplement: jci-128-96551-s001.pdf

Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics.

Wang H et al.

Journal of Translational Medicine, 2017

28810879 (PubMed )
Supplement: 12967_2017_1276_MOESM4_ESM.xlsx › Table_S2

Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Chen F et al.

Nature Communications, 2017

28775315 (PubMed )
Supplement: 41467_2017_289_MOESM7_ESM.xlsx › mutation_data

Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles.

Kim E et al.

Cancer Discovery, 2016

Spatial genomic heterogeneity within localized, multifocal prostate cancer.

Boutros PC et al.

Nature Genetics, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."