Varaico: Literature-Extracted Genetic Variants

Gene:SPOP
Variant:p.F125C
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SPOP

NM_001007228.2:p.F125C

Associated Papers

Molecular insights for the tumor suppressor role of SPOP in prostate cancer.

Yan P et al.

Biochimica Et Biophysica Acta. Reviews on Cancer, 2026

Comprehensive genomic landscape of metastatic hormone-sensitive prostate cancer in the Chinese population.

Yang B et al.

World Journal of Surgical Oncology, 2025

41121095 (PubMed )
Supplement: 12957_2025_4049_MOESM3_ESM.xlsx › Somatic_mutations

Updates on SPOP Gene Mutations in Prostate Cancer and Computational Insights From TCGA cBioPortal Database.

Zakari S et al.

Scientifica, 2025

Co-evolution of AR gene copy number and structural complexity in endocrine therapy resistant prostate cancer.

Zivanovic A et al.

Nar Cancer, 2023

37636316 (PubMed )
Supplement: zcad045_supplemental_files.zip › SupplementaryDataS12.xlsx › Sheet_1

Opposing Roles of SPOP Mutations in Human Prostate and Endometrial Cancers.

Cavalcante L et al.

Jco Precision Oncology, 2023

Genomics of lethal prostate cancer at diagnosis and castration resistance.

Mateo J et al.

The Journal of Clinical Investigation, 2020

31874108 (PubMed )
Supplement: jci-130-132031-s102.xlsx › shared_calls_primary-mCRPC

The novel BET-CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild-type prostate cancer.

Yan Y et al.

Embo Molecular Medicine, 2019

Identification of SPOP related metabolic pathways in prostate cancer.

Yan M et al.

Oncotarget, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."